TMG N,N,N′,N′-Tetramethylguanidine CAS80-70-6

TMG N,N,N′,N′-Tetramethylguanidine CAS80-70-6


CAS No.: 80-70-6


Common Name: N,N,N′,N′-Tetramethylguanidine

Other Chemical Names:

N,N’-Tetramethylguanidine;1,1,3,3-TetramethylGuanidine(TMG);1,1,3,3-Tetramethylgyanidine, 1,1,3,3-TetrChemicalbookamethylguanidine, ;N,N,N,N-Tetramethy1Guanidine; 1,1,3,3-Tetramethylguanidin; TMG; 1,1,3tetramethylguanidine

MF: C5H13N3

MW: 115.18

CAS: 80-70-6

Typical Properties:

AppearanceForm: liquidColour: light yellow
PH12.7 at 10 g/l at 25 °C
Melting point/freezing pointMelting point/range: -80 °C at 1,013 hPa
Initial boiling pointand boiling range162 – 163 °C – lit.162 °C at 1,013 hPa
Flash point50 °C – closed cup
Density0.916g/cm3 at 20℃
Vapour pressure2.9 hPa at 20 °C


In organic synthesis, 1,1,3,3-tetramethylguanidine is used as a strong, non-nucleophilic base. 1,1,3,3-tetramethylguanidine is an efficient and selective catalyst for alcohol benzoylation.

Physical and chemical properties tetramethylguanidine is a colorless oily liquid, boiling point 160-162℃, density 0.918, refractive index 1.4692, is a strong organic base, soluble in toluene, cyclohexanone, ethanol, etc., also Chemicalbook soluble in water, easily hydrolyzed to tetramethyl urea in alkaline aqueous solution, corrosive, generally packed in galvanized iron drums.


NT CAT TMG can also be used as a catalyst for polyurethane foam and for even dyeing of nylon, wool and other proteins to improve the durability of wool, etc. It is mainly used in the synthesis of cefradine and other drugs.

Storage Information

NEWTOP Chemical recommends that our catalysts be stored in a dry and cool area under appropriate ventilation conditions. Each container should be closed tightly to avoid contamination with moisture or other negative influences that could change the products’ performance in the end use. The optimum storage temperature is between 10 °C and 30° C. Lower and higher storage temperatures are not preferable and should be avoided.

Shelf Life:

24 Months

Standard Packaging:

180KG Steel Drum

900KGl IBC Drum

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